Mrs Jones went to see her GP as she had noticed she had lost weight even though she felt she was eating more. On examination Mrs Jones had sweaty, erythematous plams, a rapid and bounding pulse and upper lid retraction.

Following further examination and investigations a diagnosis of Graves' disease was made, which of the following is most closely linked with Graves' disease?

A) Diarrhoea

B) Increased free T3

C) Dysphagia

D) Fever

E) Pretibial myxoedema

Which of the following statements best defines a fibroadenoma:

A) Smooth, spherical or elliptical mass.
B) Firm and lumpy mass with large lobules.
C) Can present at any age, but more common in old age.
D) Often associated with lactation.
E) Warm and erythematous mass.

Proteinuria (>3g/24h), odema and hypoalbuminaemia (albumin <25g/L) is the classical triad of signs for which of the following conditions?

A) Nephritic syndrome
B) Urinary tract infection
C) Acute renal failure
D) Nephrotic syndrome
E) Over use of potassium-sparing diuretics

Which of the following is true about Warfarin?

A) Warfarin inhibits Vitamin E dependant clotting factors 6 and 8.
B) Warfarin promotes production of endogenous anticoagulants such as protein S.
C) Warfarin inhibits carboxylation of clotting factors 9 and 10.
D) Warfarin inhibits only the extrinsic pathway and so Heparin is commonly prescribed as well.
E) Warfarin is used in the acute setting for thrombolysis.

With regards to anaemia, which of the following is correct?

A) Folate deficiency causes a macrocytic anaemia.

B) Sickle cell disease commonly presents with fatigue due to haemolysis of red blood cells.

C) Normocytic anaemia does not have a malignant cause.

D) Iron deficiency is a rare cause of microcytic anaemia.

E) Acute blood loss results in a microcytic anaemia.

Which of the following findings is the strongest predictive factor for pulmonary embolus?

A) Dyspnoea

B) Fever

C) Haemoptysis

D) Heart rate over 100 beats per minute

E) Known malignancy